a Record control number 000323845500004

a ISSN 0959-2989

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number QT 36

b Item number .S96 2013

a Personal name Adalı, Terin,

h Medium Electronic Document

a Title Synthesis and characterization of noncytotoxic and biodegradable polymethacrylates-grafted chitosan gels.

c Statement of responsibility, etc Terin Adalı.

b Name of publisher, distributor, etc IOS,

c Date of publication, distribution, etc 2013.

a Place of publication, distribution, etc Amsterdam :

a Summary, etc Poly(methacrylates), namely 2-hydroxy ethyl methacrylate (HEMA), ethylene glycol dimethacrylate (EGDMA) and triethylene glycol dimethacrylate (TEGDMA) were grafted onto chitosan by using ceric ammonium nitrate as a redox initiator. Semi-IPN gels of chitosan-graft-poly(HEMA)-graft-poly(EGDMA) and chitosan-graft-poly(HEMA)-graft-poly(TEGDMA) were obtained. The grafting conditions were optimized with respect to monomer concentrations. The products were characterized by TGA, FTIR, XRD and SEM techniques. The solubility of the grafted products in aqueous medium decreased with increasing grafting percentage. The insoluble gels exhibited a highly pH sensitive swelling behaviour. TGA thermograms showed that poly(HEMA)/poly(TEGDMA)-grafted product is much more stable than poly(HEMA)/poly(EGDMA)-grafted product showing that TEGDMA is a more effective crosslinker than EGDMA. According to XRD analysis TEGDMA has a higher tendency to form ordered structures than EGDMA as it is capable of chain folding. The results of cytotoxicity studies revealed that the methacrylate-grafted chitosans were noncytotoxic and good candidates for biomedical applications.

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element Biomedical

a Topical term or geographic name as entry element Biomedical Engineering

a Topical term or geographic name as entry element Chitosan

a Topical term or geographic name as entry element Grafting

a Topical term or geographic name as entry element Poly(methacrylates)

a Topical term or geographic name as entry element Cytotoxicity

a Topical term or geographic name as entry element Biodegradability

g Relationship information 2013, Vol 23 Issue 5 p349-359

t Title Bio-Medical Materials And Engineering

x International Standard Serial Number 09592989

u Uniform Resource Identifier http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.3233/BME-130759